Evaluation of the frequency ,type,specifications and complications caused by treatment in infants with retinopathy of prematurity referred to Khatam Al Anbia Hospital in Mashhad from 1397-1400
Mohammad reza Ansari Astaneh1 *, Mahshid Sadeghi1 , Majid Abrishami1 , Naser Shoeibi1 , Mojtaba Abrishami1 , Elham Bakhtiari1
- Eye research center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract: To investigate the rate, type, complications and specification of treatment and retreatment in ROP patients in our center.
Methods: In a cross-sectional study, premature infants who were visited in the ROP clinic of Khatam Mashhad Hospital from 1397-1400 and were treated entered the study.
Results: From 10,159 infants referred to the retinopathy of prematurity clinic from 2018 to the end of 2021; 5008 people (49.29%) were suffering from ROP, of which 416 (8.3%) patients needed treatment for retinopathy of prematurity. The average birth age and weight of the patients under study was 28.66 ± 2.24 weeks. and1227.24 ± 375.97 grams. In the first round of treatment, 96.4% (738 eyes) of the patients' eyes received Avastin injection. 3% were lasered (23 eyes) and vitrectomy was performed for 0.5% of patients' eyes. Bilateral ingection was done in 84.03% (337 people) unilateral injection in 15.96%.3.6% of patients (15 patients) nedded retreatment because of relapse and the mean time between first and second treatment was 60.58 days. Only 4 patients needed retreatment after first relapse. The type of retreatment in the first relapse was Laser in 70.4% of eyes and reinjection in 11.0 % of eyes and viterectomy in one eye and scleral buckling in one eye. 9 eyes had two relapses who underwent Laser in 8 eyes and vitrectomy in one eye. The results of the study showed that there is a significant relationship between birth age and ROP recurrence (P=0.001) or oxygen time (P=0.01). In the age group of less than 28 weeks, the average age of the off time was higher than the age groups of 28 to 30 weeks and 30 to 34 weeks (p=0.04). Of the patients who were treated, 3 patients developed cataracts and 1 patient developed vitreous bleeding
Conclusion: In patients with a younger birth age and a longer duration of oxygen therapy, the treatment should be done with more supervision and precision.
