Investigating the demographic characteristics , incidence rates and risk factors in infants referred to the retinopathy of prematurity screening clinic of Khatam al-Anbia hospital in Mashhad since 2012-2019.

Mohammad reza Ansari Astaneh1 *, Sadegh Nazif1 , Naser Shoeibi2 , Majid Abrishami1 , Mojtaba Abrishami1 , Elham Bakhtiari1 , Mehdi Sakhayee1

  1. Eye research center, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 1Eye research center, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract: This study has been carried out to identify demographic characteristics, risk factors and the number of examinations per baby as well as the risk factors of retinopathy of prematurity in screening clinic of Khatam al-Anbia hospital in Mashhad since 2012-2019.

Methods: in a cross-sectional study all premature infants who visited the ROP clinic of Khatam Al-Anbia Hospital from 2012-2019, in terms of ROP risk factors (birth age, birth weight, twins and multiples, treatment with oxygen and duration of hospitalization in NICU) and demographic characteristics and incidence rates were investigated. Required information such as gestational age, patient's weight and all the information recorded in the registry software available in the clinic and patients' files were extracted and analyzed using statistical methods.

Results: In this study, the information of 11147 patients with ROP was analyzed. The average age of the initial examination of the patients was 34.4±.6.45 weeks .and the average gestational age of was 32.4 ± 2.97 weeks. On average, the patients were treated with oxygen for 3.68 ± 9.09 days. 92.2% (8983 people) of the patients were preterm. Overly 22294 eyes were examined, in which the frequency of ROP was 42.07% (9380 eyes) and the frequency of PLUS disease in the first visit was 1.6% (359 eyes). Other findings in the first visit include bleeding (1.2%), pigmentation (0.08% eyes), scar (0.06% eyes), and cataract (0.06% eyes). A total of 374 eyes (98.3%) of all eyes with ROP were treated. Statistical studies showed that with the increase in the Stages of ROP, the duration of oxygen therapy and the duration of patients in the NICU section also increased (P=0.0001).

Conclusion: The number of litters, birth weight, and birth age and oxygen intake are the most important risk factors for developing the disease.





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