Short-term effects of pan-retinal photocoagulation on the optic nerve head neurovasculature
Mohammad reza Ansari Astaneh1 *, Nasim Shahsavan1 , Mojtaba Abrishami1 , Mehrdad Motamed Shariati1
- Eye research center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract: We aimed to evaluate the changes in the optic nerve head (ONH) blood flow and tomographic profile during 1 month following pan-retinal photocoagulation (PRP) using optical coherence tomography angiography (OCTA).
Methods: Thirteen patients with early PDR stage were enrolled in this longitudinal study. Patients with any history of any other ONH disease or treatment effort for diabetic retinopathy have not participated in this study. All participants underwent a complete ophthalmic examination and ONH optical coherence tomography angiography (AngioVue RTVue XR Avanti, Optovue, Fremont, CA, USA, software version: 2018,0,0,18) with a 4.5*4.5 mm scan size before and in different periods after PRP (one hour, one week, and one month). The ONH vascular and tomographic profiles were analyzed.
Results: The mean± Sd of the patient’s age was 55.25±9.28. Based on the results of this study, changes in ONH vascular profile in PDR patients before and in different periods after PRP were not statistically significant. There was no statistically significant change in the ONH tomographic profile including cup/disc ratio, rim area, disc area, and cup volume. Repeated measure analysis showed a significant change in the peripapillary RNFL thickness during the study period
Conclusion: We concluded that the peripapillary RNFL thickness goes through a significant fluctuating course during the first month following PRP.
