Evaluation of macular vasculature following pan-retinal photocoagulation in diabetic retinopathy using optical coherence tomography angiography

Mohammad reza Ansari Astaneh1 *, Nasim Shahsavan Gharbi1 , Mojtaba Abrishami11 , Elham Bakhtiari1 , Mehrdad Motamed Shariati2

  1. Eye research center, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 1. Eye research center, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract: To evaluate the changes in the macular flow profile during 1 month following pan-retinal photocoagulation (PRP) using optical coherence tomography angiography (OCTA).

Methods: Thirteen patients with early PDR stage were enrolled in this longitudinal study. Patients with any history of any other macular disease or treatment effort for diabetic retinopathy have not participated in this study. All participants underwent a complete ophthalmic examination and macular optical coherence tomography angiography (AngioVue RTVue XR Avanti, Optovue, Fremont, CA, USA, software version: 2018,0,0,18) with a 6 * 6 mm scan size before and in different periods after PRP (one hour, one week, and one month). Superficial and deep capillary plexus were analyzed.

Results: : The mean± Sd of the patient’s age was 55.25±9.28. Based on the results of this study, changes in macular superficial vessel density (SVD), deep vessel density (DVD), and foveal avascular zone (FAZ) area in PDR patients before and in different periods after PRP were not statistically significant.

Conclusion: PRP in patients with early PDR stage of diabetic retinopathy did not have a significant effect on the macular vasculature during the first month of treatment.





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